多肽与金属离子发生螯合的先决条件是多肽能够为金属离子提供电子对，肽的末端羧基或氨基中含有比较多的氮原子、氧原子和硫原子，铁离子可与多肽在氨基、羧基等位点发生配位，以共价键形式结合。在肽铁螯合机理的表征中，肽铁结合的本质是亚铁离子与多肽中特定的化学基团发生反应。通过傅里叶变换红外光谱、质谱、核磁共振光谱等，比较金属离子结合前后红外吸收峰和波长的变化来识别肽的结合基团。多肽侧链中的氮原子、氧原子、硫原子，可以提供孤对电子与亚铁离子结合，氮原子是亚铁离子的主要结合位点。通过红外光谱研究黄皮种子抗氧化肽铁螯合物的结合位点，发现主要通过羧基氧、氨基氮原子与亚铁离子结合。虽然已经有很多关于肽铁螯合位点的相关研究，但对肽铁螯合的结构关系和动力学过程还需要更深入的探索。

公司官网：www.wilincare.net欢迎选购！

抗坏血酸亚铁Ferrous Ascorbate、赖氨酸甘氨酸镁Magnesium Lysinate Glycinate、甘氨酸谷氨酰胺镁Magnesium Glycinate Glutamine、柠檬酸苹果酸镁Magnesium Citrate Malate、柠檬酸锶Strontium Citrate、柠檬酸锰Manganese Citrate、柠檬酸铜Copper Citrate、天门冬氨酸锂Lithium Aspartate、抗坏血酸锰Manganese Ascorbate、牛磺酸硒Selenium Taurate。

Mechanism of chelation of polypeptides with ferrous

The prerequisite for chelating polypeptides with metal ions is that polypeptides can provide electron pairs for metal ions. The terminal carboxyl group or amino group of peptides contains more nitrogen atoms, oxygen atoms and sulfur atoms, and iron ions can coordinate with polypeptides at amino and carboxyl groups and other sites to combine in the form of covalent bonds. In the characterization of peptide iron chelation mechanism, the essence of peptide iron binding is that ferrous ions react with specific chemical groups in peptides. By Fourier transform infrared spectroscopy, mass spectrometry and nuclear magnetic resonance spectroscopy, the changes of infrared absorption peak and wavelength before and after metal ion binding were compared to identify the binding groups of peptides. Nitrogen atoms, oxygen atoms and sulfur atoms in the side chain of the polypeptide can provide lone pair electrons to bind to ferrous ions, and nitrogen atoms are the main binding sites of ferrous ions. The binding sites of iron chelate of antioxidant peptide in Xanthophylla seeds were studied by infrared spectroscopy. It was found that the binding sites of ferrous ions were mainly through carboxyl oxygen and amino nitrogen atoms. Although there have been many studies on the iron chelation sites of peptides, the structural relationship and kinetic process of peptide iron chelation still need to be further explored.

Company's official website: www.wilincare.net welcome to buy!

Ferrous Ascorbate, Magnesium Lysinate Glycinate, Magnesium lysinate Glycinate Glutamine, Magnesium citrate malate Citrate Malate, Strontium Citrate, Manganese Citrate, Copper Citrate, Lithium Aspartate, Manganese ascorbate Ascorbate, Selenium Taurate.